Haemato-biochemical Effects of Aqueous Extract of Khaya senegalensis Stem Bark on Gentamicin-Induced Nephrotoxicity in Wistar Rats

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Effect of Aqueous Stem Bark Extract of Khaya senegalensis on Some Biochemical, Haematological, and Histopathological Parameters of Rats

The subchronic effect of aqueous stem bark extract of Khaya senegalensis on some biochemical, haematological, and histopathological parameters of rats was investigated. The rats were divided into six groups of five rats per group. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. The result of study revealed that administration of the Kha...

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Potency of Aqueous Stem Bark Extract of Khaya Senegalensis against Liver Diseases in Rats

In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl4. The rats treated with a daily dose of...

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Protective Effects of Cinnamon Bark Hydroalcoholic Extract on Gentamicin-induced Nephrotoxicity in Mature Rats

Background and Methodology: Gentamicin is a broad-spectrum antibiotic with restricted application in man and stock due to its side effects such as Nephrotoxicity and autotoxicity. Cinnamon bark has antioxidant properties. This is the first study on the protective effects of the hydroalcoholic extract of cinnamon on gentamicin-induced nephrotoxicity.Methods and Materials: Thirty-six mature femal...

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Protective Effects of Cinnamon Bark Hydroalcoholic Extract on Gentamicin-induced Nephrotoxicity in Mature Rats

Background and Methodology: Gentamicin is a broad-spectrum antibiotic with restricted application in man and stock due to its side effects such as Nephrotoxicity and autotoxicity. Cinnamon bark has antioxidant properties. This is the first study on the protective effects of the hydroalcoholic extract of cinnamon on gentamicin-induced nephrotoxicity.Methods and Materials: Thirty-six mature femal...

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ژورنال

عنوان ژورنال: Journal of Biological Sciences

سال: 2012

ISSN: 1727-3048

DOI: 10.3923/jbs.2012.361.366